When the sādhaka performs sādhana under the expert guidance of a bona fide guru, in course of time these six enemies will be killed. All these desires for mundane enjoyment will gradually vanish and the sādhaka will develop a higher taste. When the sādhaka attains the śuddha-sattva stage, Krishna will appear. Otherwise, as long as these things are there, how can one make Krishna appear? It is impossible. You cannot develop love for Krishna and you cannot be attracted to Krishna unless these six things are destroyed.